What's Up, Doc?

Barbra Streisand

Judy Maxwell

Ryan O'Neal

Howard Bannister

Madeline Kahn

Eunice Burns

Kenneth Mars

Hugh Simon

Austin Pendleton

Frederick Larrabee

Michael Murphy

Mr. Smith

Philip Roth

Mr. Jones

Sorrell Booke

Harry

Stefan Gierasch

Fritz

Mabel Albertson

Mrs. Van Hoskins

Liam Dunn

Judge Maxwell

John Hillerman

Hotel Manager

George Morfogen

Headwaiter

Graham Jarvis

Bailiff

Randy Quaid

Professor Hosquith

M. Emmet Walsh

Arresting Officer

Kevin O'Neal

Delivery Boy

Eleanor Zee

Banquet Receptionist

Paul Condylis

Room Service Waiter

Fred Scheiwiller

Jewel Thief

Carl Saxe

Jewel Thief

Jack Perkins

Jewel Thief

Paul B. Kipilman

Druggist

Gil Perkins

Jones' Driver

Christa Lang

Mrs. Hosquith

Stan Ross

Musicologist

Peter Eastman

Musicologist

Eric Brotherson

Larrabee's Butler

Elaine Partnow

Party Guest

George Burrafato

Eunice's Cab Driver

Jerry Summers

Smith's Cab Driver

Mark Thompson

Airport Cab Driver

Don Bexley

Skycap

Leonard Lookabaugh

Painter on Roof

Candace Brownell

Ticket Seller

Sean Morgan

Banquet Official

Patricia O'Neal

Lady on Plane

Joe Alfasa

Waiter in Hall

Chuck Holison

Pizza Cook

Cosmo Sardo

Hotel Waiter (uncredited)